A hypoxia-responsive tRNA-derived small RNA confers renal protection through RNA autophagy
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Transfer RNA-derived small RNAs (tsRNAs, or tDRs) perform a range of cellular functions. Here, we showed that a hypoxia-induced tDR, derived from the 3' end of tRNA-Asp-GTC (tRNA-Asp-GTC-3'tDR), activated autophagic flux in kidney cells, while its silencing ... ...