Blockade of Gi Signaling Enhances the Anabolic Effect of Parathyroid Hormone in Female Mice
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Intermittent administration of parathyroid hormone (PTH) produces potent anabolic effects on bone. These anabolic effects appear to be mediated by activation of the Gs-cyclic AMP system initiated by the PTH1 receptor (PTHR1) in osteoblast lineage cells. Gs-med... ...
