Fertility is compromised after oocyte-specific deletion of microtubule severing protein katanin A1
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Katanins are microtubule severing enzymes that play roles in diverse cell functions including meiotic and mitotic spindle formation. To address the role of Katanin p60 isozymes in mammalian oocytes, we have used the ZP3-CreLox approach to specifically delete K... ...
