Klotho promotes autophagy and alleviates cyclophosphamide-induced ovarian granulosa cell injury by activating AMPK/ULK1 signaling pathway
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Premature ovarian insufficiency (POI) seriously affects women's reproductive health. This study aims to explore the mechanism of Klotho-mediated autophagy in alleviating POI. Cyclophosphamide (CTX) treated COV434 cells and CTX injection induced POI mouse mode... ...