A leucine derivate-adjuvanted LNP vaccine enhances antitumor immunity through mTOR activation and metabolic reprograming in dendritic cells
{{output}}
Neoantigen-derived peptide vaccines have been emergingly employed to treat tumors, however, their inefficient delivery and antigenicity remain challenging. In this study, for the first time a leucine derivate LLOMe (L-leucyl-l-leucine methyl ester) was repurpo... ...
