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Polystyrene nanoplastics promote muscle cell senescence through microtubule hyper-stabilization-mediated mitophagy dysfunction and cGAS-Sting activation

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The detrimental effects of polystyrene nanoplastics (NPs) on human skeletal muscle cells and underlying mechanisms remain largely unclear. Here we exposed mice to NPs and observed significant NP uptake and damages in muscles. RNA sequencing result revealed tha... ...