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Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability

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Mature neocortical pyramidal cells functionally express two sodium channel (NaV) isoforms: NaV1.2 and NaV1.6. These isoforms are differentially localized to pyramidal cell compartments, and as such are thought to contribute to different aspects of neuronal exc... ...