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Molecular mechanism differences between nanoplastics and microplastics in colon toxicity: nanoplastics induce ferroptosis-mediated immunogenic cell death, while microplastics cause cell metabolic reprogramming

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This study investigates the size-dependent mechanisms by which polystyrene (PS) microplastics (MPs) cause intestinal epithelial injury, focusing on the differential effects of nanoscale (100 nm) and microscale (10 μm) particles. Using both cellular and animal... ...