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Enzyme-induced fluorescence signal-on for specific detection of alkaline phosphatase and imaging in live cells

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A highly sensitive and stable fluorescent strategy for detecting alkaline phosphatase (ALP) in complex samples was developed using oxidized single-walled carbon nanohorns (oxSWCNHs) and exonuclease I (Exo I). A ssDNA probe, comprising a fluorophore-labeled apt... ...