Low level of expression of known deafness genes Kcne1, Kcnj10 or Col4a3 is sufficient to maintain hearing in mice
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Kcne1, Kcnj10 and Col4a3 are all expressed in the stria vascularis where they serve critical roles in generating the endocochlear potential. Mutations in any of these three genes are linked to human deafness syndromes for which there are currently no treatment... ...