Isa2p is essential in Saccharomyces cerevisiae for mitochondrial function and stress resistance by allowing Rip1p subunit assembly into cytochrome bc1 complex
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In Saccharomyces cerevisiae, the iron-sulfur cluster biogenesis late-acting subsystem (Fe-S-IBG) comprises the mitochondrial glutaredoxin (Grx5), Isa1, Isa2, and iron-sulfur cluster assembly factor IBA57 (Iba57) proteins. The Fe-S-IBG subsystem assists in inse... ...