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Novel Urazole-Derived MS-Cleavable Cross-Linkers Targeting Tyrosine/Lysine Residues for Protein Structural Analysis

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Chemical cross-linking mass spectrometry (XL-MS) is crucial for probing protein structure and protein-protein interactions. Currently, lysine-reactive cross-linkers have been widely developed and applied. In this study, two urazole-derived MS-cleavable cross-l... ...