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Endothelial cell STING regulates IL6 production and is required for pathological cardiac hypertrophy and contractile dysfunction in experimental heart failure

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Capillary rarefaction and cardiomyocyte (CM) hypertrophy are hallmarks of the complex syndrome of heart failure (HF), a leading cause of hospitalization and death. Molecular signals within and between cellular components of the heart have emerged as central hu... ...