CFTR-Independent Prostaglandin E2-Stimulated Chloride Secretion in Human Airway
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Background: Prostaglandin E2 (PGE2) is a potent stimulator of airway epithelial Cl- secretion. PGE2 can stimulate CFTR-independent Cl- secretion from Calu-3 submucosal gland cells, whereas human bronchial epithelial (HBE) cells require CFTR. Aim: Determine the... ...