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Emergence of a conjugative hybrid plasmid co-harboring mcr-1.1, mcr-3.39, and tet(X4) in Escherichia coli from wastewater in Seoul: A potential threat to last-line antibiotics

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The emergence of plasmid-mediated antimicrobial resistance to last-line antibiotics such as colistin and tigecycline poses an escalating public health threat. In this study, we identified an Escherichia coli strain (WWCOL-256) isolated from municipal wastewate... ...