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Single-cell spatial transcriptomics reveals immunotherapy-driven bone marrow niche remodeling in AML

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Given the graft-versus-leukemia effect observed with allogeneic hematopoietic stem cell transplantation in refractory or relapsed acute myeloid leukemia (AML), immunotherapies have been explored in nontransplant settings. We applied a multiomic approach to exa... ...