Biocatalytic Alkylation of Ambident Nucleophiles Enables Selective N‑Functionalization of Heterocycles and Late-Stage Modifications
{{output}}
The alkylation with electrophilic haloalkanes is a key methodology in chemical synthesis to build desired molecules. While alkylation of compounds bearing a single nucleophilic site is routine, the selective alkylation of polyfunctional molecules with multiple... ...
