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The microbial metabolite isovaleric acid aggravates gelatinase-mediated periodontal tissue destruction via the NF-κB signaling pathway

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Background: Isovaleric acid, an important short-chain fatty acid, can be generated by subgingival microbial fermentation of a leucine-rich diet, such as Porphyromonas gingivalis. This study aimed to explore the impact of isovaler... ...