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Function and firing of the Streptomyces coelicolor contractile injection system requires the membrane protein CisA

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Bacterial contractile injection systems (CIS) are phage tail-like macromolecular complexes that mediate cell-cell interactions by injecting effector proteins into target cells. CIS from Streptomyces coelicolor (CISSc) are localized in the cytoplasm. Under stre... ...