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Investigating Intestinal Farnesoid X Receptor functions at the Intestinal Mucosal Barrier and in the Intestinal Microbiota in a Biliary Obstruction Mouse Model

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Intestinal barrier dysfunction and dysbiosis are critical intestinal alterations in biliary obstructive diseases, for which FXR is a potential intestinal therapeutic target, but its roles and mechanisms in the intestinal tract remain poorly defined. Using gut-... ...