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Untangling the causes of geographical disparities in the clinical outcome of HTLV-1 infection: a critical perspective on the contribution of viral genetic diversity

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Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) is the etiological agent of two major diseases, adult T-cell leukemia/lymphoma (ATLL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), as well as various other inflammatory manifestat... ...