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Bottom-up structural analysis of amides by identifying collision-induced dissociation fragment ions: An application in bile acid-amino acid conjugates-targeted sub-metabolome profiling

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Background: Amide serves as the key functional group for several chemical families, such as proteins, peptides, amides, and amino acid-conjugated bile acids (AA-BAs), and the featured fragment ions (e.g., a+/-, b+/-, c+/-, x+/-, ... ...