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TEK-related venous malformation of the orofacial region: report of a case with multidisciplinary treatment guided by molecular diagnosis

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Vascular malformations (VMs) often affect the orofacial region, where they can markedly impact the quality of life. They frequently harbor mutations in TEK, PIK3CA, or other genes essential for angiogenesis. Alpelisib is a phosphatidylinositol 3-kinase inhibit... ...