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The PE/PPE family proteins of Mycobacterium tuberculosis: evolution, function, and prospects for tuberculosis control

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Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading global health threat, exacerbated by drug resistance and inadequate vaccine efficacy. The PE/PPE protein family, unique to mycobacteria, constitutes ~10% of the Mtb genome and pla... ...