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Exploring the effects of food by-product HMF on pepsin structure, function, and physiological activity from a binding perspective

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5-Hydroxymethylfurfural (HMF) derived from the Maillard reaction poses significant health risks including neurotoxicity and carcinogenicity. Upon ingestion with food, HMF can interact with pepsin, a pivotal enzyme in the human digestive system. This study expl... ...