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Taraxerol induces ferroptosis in breast cancer by targeting Nrf2 transcriptional activity to promote MIB2-mediated GPX4 ubiquitination

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Background: Eradicating tumors through targeted ferroptosis represents a novel approach to BC treatment. Taraxerol, a natural triterpenoid derived from dandelions, has shown anti-tumor effects. However, the ferroptosis dependency... ...