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Synthesis of β-ketophosphonates through aerobic copper(II)-mediated phosphorylation of enol acetates

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Aerobic copper(II)-mediated phosphorylation of enol acetates with H-phosphonates leading to the formation of β-ketophosphonates was discovered. The proposed method is applicable to a wide range of H-phosphonates or phosphine oxides as PH-reagents and enol ace... ...