Pseudouridine RNA avoids immune detection through impaired endolysosomal processing and TLR engagement
{{output}}
Recognition of exogenous RNA by Toll-like receptors (TLRs) is central to pathogen defense. Using two distinct binding pockets, TLR7 and TLR8 recognize RNA degradation products generated by endolysosomal nucleases. RNA modifications present in endogenous RNA pr... ...
