Inhibition of SREBP-1c Rescues Hepatic CYP7B1 Expression and Bile Acid Synthesis in Malnourished Mice
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Malnutrition decreases intestinal bile acids, resulting in inefficient nutrient absorption and impaired catch-up growth. Mechanisms by which bile acid depletion occurs in malnutrition are unknown. Using a mouse model of early-life malnutrition, we explored bil... ...