Extracellular Matrix Topography Drives Adrenergic to Mesenchymal Transition in Neuroblastoma
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Neuroblastoma (NB), the most common extracranial solid tumor in children, exhibits intra-tumoral heterogeneity with two interconvertible identities: adrenergic (ADRN) and mesenchymal (MES). Compared to ADRN cells, MES cells exhibit phenotypes associated with m... ...
