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HSV1 glycoprotein D utilizes an LY6-like binding domain to inhibit alpha7 nicotinic receptors

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Herpes virus1(HSV1) is a neurotropic virus that has been linked to Alzheimer's disease. An In-silico structural homology search using α -Bgtx, identified structural homology between HSV1 gD and the nicotinic receptor neurotoxin α-Bgtx. SPR binding studies u... ...