GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity
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Biased agonism of G protein-coupled receptors (GPCRs) offers potential for safer medications. Current efforts have explored the balance between G proteins and β-arrestin; however, other transducers like GPCR kinases (GRKs) remain understudied. GRK2 is essenti... ...
