Characterization of organic anion transporting polypeptide (OATP)1B1 and OATP1B3 humanized rat as a translational model to study the pharmacokinetics of OATP1B substrate drugs
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Organic anion transporting polypeptide (OATP)1B1 and OATP1B3 (OATP1B) are clinically important transporters that mediate active hepatic uptake for a broad range of drugs and endogenous compounds and play a pivotal role in hepatic disposition and drug-drug inte... ...