The role of Nef in the long-term persistence of the replication-competent HIV reservoir in South African women
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HIV-1 Nef mediates immune evasion and viral pathogenesis in part through the downregulation of cell surface cluster of differentiation 4 (CD4) and major histocompatibility complex class I (MHC-I) on infected cells. While the Nef function of circulating viral p... ...
