TRPV4 activation by TGFβ2 enhances cellular contractility and drives ocular hypertension
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The risk for developing primary open-angle glaucoma (POAG) correlates with the magnitude of ocular hypertension (OHT) and the concentration of transforming growth factor-β2 (TGFβ2) in the aqueous humor. Effective treatment of POAG requires a detailed underst... ...