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Mechanism of trypsin-mediated differentiation of pancreatic progenitor cells into functional islet-like clusters

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Background: Endogenous regeneration of pancreatic islet β-cells is a path to cure both type 1 and advanced type 2 diabetes. Pancreatic cancer cell line-1 (PANC-1), a human pancreatic islet progenitor cell line, can be induced by... ...