ABCG2 protein expression in tumors of patients with non-resectable pancreatic cancer treated with gemcitabine and nab-paclitaxel
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Background: ATP-binding cassette (ABC) proteins are transmembrane efflux pumps that play a role in Multi Drug Resistance. ABCG2 and ABCB1 have been suggested as important mediators of resistance to chemotherapy (CTx) in pancreati... ...