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Unveiling the dual role of circulating tumor cells in colorectal cancer immunotherapy: a comprehensive review of biomarker utility and immune microenvironment crosstalk

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Colorectal cancer (CRC) has the highest incidence in the Asia-Pacific region, accounting for 51.8% of global cases. Despite early screening methods like colonoscopy, CT, and MRI, 20-25% of patients are diagnosed at advanced stages, with some having liver metas... ...