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Identification of human hepatic UDP-glucuronosyltransferases involved in the glucuronidation of temazepam

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Temazepam is a commonly used 1,4-benzodiazepine that exists as a racemic mixture of R and S enantiomers that are metabolized primarily by glucuronidation via the UDP-glucuronosyltransferases (UGT) enzymes. The goal of the present study was to identify the indi... ...