BEZ235-Mediated PI3K/mTOR dual inhibition improves ovarian follicle survival in a preclinical model
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Background: Follicular loss after ovarian tissue cryopreservation and autotransplantation (OTCTP) remains a major challenge due to follicle activation and ischemia. We evaluated BEZ235, a dual PI3K/mTOR inhibitor, as a strategy t... ...