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Study about fluostatins: efficient preparation of fluostatin A and discovery of fluostatin derivatives from Streptomyces sp. TA-3391

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Fluostatins are a class of compounds having four unique ring systems. They were originally isolated as dipeptidyl peptidase III (DPP3) inhibitors, and various derivatives and activities have been reported. In this study, fluostatin A, which is difficult to pre... ...