Vitex negundo L. var. cannabifolia (VN) is a traditional Chinese medicine (TCM) and has long been used for rheumatic arthralgia and rheumatoid arthritis. However, pharmacological and mechanistic studies confirming these clinical effects have not yet been published. This study compared the anti-inflammatory and analgesic effects of different medicinal parts of VN. The root, stems and leaves, and fruit of VN were refluxed with 70 % ethanol to obtain the VNR,... ...

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