Design, synthesis, and biological evaluation of bergapten derivatives as potent anti-pancreatic cancer agents
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Bergapten, a natural product from Zanthoxylum bungeanum Maxim., exhibits anticancer, antibacterial, anti-inflammatory, and hypolipidemic effects. A derivative, FSG-Y5 showed potent activity against pancreatic cancer cells PANC-1 (IC50 = 2.31 ± 0.25 µM) and C... ...