STAT1-mediated epigenetic regulation of LIN28A controls iPSC-derived platelet production through the let-7-RALB axis
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Ex vivo platelet production from induced pluripotent stem cells (iPSCs) represents a potential solution to address the limitations of donor-dependent platelet transfusion therapy. While our established immortalized megakaryocyte progenitor cell lines (imMKCLs)... ...
