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Intracellular and nuclear CXCR4 signaling promotes terminal erythroblast differentiation and enucleation

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The chemokine CXCL12 signals through its receptor CXCR4 to induce the migration of all leukocyte types and multiple other cell types. Here, we report that CXCR4 is expressed in mouse erythroblasts, the bone marrow erythroid precursors, in which it stimulates e... ...