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Synthesis and Multidisciplinary Preclinical Investigations of Ferrocenyl, Ruthenocenyl, and Benzyl Derivatives of Thiabendazole as New Drug Candidates against Soil-Transmitted Helminth Infections

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An estimated 1.5 billion people worldwide are infected with at least one parasitic nematode species classified as soil-transmitted helminths (STHs). The recommended control strategy is to reduce morbidity using a single oral dose of the benzimidazole drugs, al... ...