Medical science monitor : international medical journal of experimental and clinical research. 2025 Jun 16:31:e947157. doi: 10.12659/MSM.947157 Q32.12025
Effects of Weight Loss on Insulin Resistance and Liver Health in T2DM and NAFLD Patients
体重减轻对2型糖尿病和非酒精性脂肪肝患者胰岛素抵抗和肝脏健康的影响 翻译改进
Xu Yang 1, Qifang Meng 1, Pingyu Wu 1
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DOI: 10.12659/MSM.947157 PMID: 40522909
摘要 中英对照阅读
背景：T2DM和MASLD（非酒精性脂肪肝病）共病的增加，主要是由胰岛素抵抗（IR）驱动的，强调了有效干预措施的需求。本研究评估了为期3个月的结构化生活方式干预对T2DM-MASLD患者肝脏脂质沉积、胰岛素抵抗及代谢参数的影响。 材料与方法：37名患者接受了个性化低热量饮食和运动计划。通过MRI-PDFF（磁共振成像-质子密度脂肪分数）量化肝脏脂肪含量，并在基线和干预后评估生化参数和HOMA-IR。参与者被分为符合规定（≥5%体重减轻，n=26）和不符合规定组（
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