Properties of Acute Activation and Inhibition of the β3 Homomeric GABAA Receptor Mediated by Protonation of Conserved Histidine Residues
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GABAA receptors are inhibitory transmitter-gated ion channels formed of various combinations of the 19 homologous subunits cloned to date. Changes in extracellular pH have been shown to directly activate the receptor or modulate its activity elicited by a chem... ...