Ultra-sensitive DNA detection with single-base mismatch resolution using graded hollow-core optical microcavity functionalized by polyA-AuNPs
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A graded hollow-core optical microcavity (GHCOM) functionalized by polyA-AuNPs is proposed and demonstrated for DNA hybridization detection with ultra-low limit of detection (LoD) and high specificity. The GHCOM with wall thickness of ∼2 μm and Q factor of 7... ...
