Methamphetamine is a derivative of amphetamine and is widely abused across the globe. It is highly addictive and acts as a potent stimulant of the central nervous system (CNS). Due to its lipophilic nature, methamphetamine easily crosses the blood-brain barrier, leading to significant neurological dysfunctions and even neuronal degeneration. The clinical signs and symptoms of methamphetamine intoxication can vary considerably depending on factors such as the dose ingested, route of administration, duration of exposure (acute and/or chronic), and method of use. Common clinical manifestations include euphoria, increased energy, insomnia, anxiety, substance-induced psychosis, decreased appetite, weight loss, heightened self-confidence, increased libido, fever, tachycardia, sweating, hypertension, tremors, mydriasis, blurred vision, and seizures. Children are particularly vulnerable, as their metabolism and nervous systems are more sensitive compared to adults, making the toxic effects more pronounced. Accidental ingestion of drugs and other substances is a frequent occurrence in pediatric populations and can lead to severe health complications. Therefore, it is crucial for healthcare professionals to promptly and accurately evaluate and manage such poisoning cases. This case report presents the clinical findings, diagnostic process, and treatment management of a one-year-old male child who accidentally ingested crystal methamphetamine orally. Additionally, the report highlights key aspects of effective case management, emphasizes preventive measures to reduce the risk of accidental drug and substance ingestion in children, and aims to raise awareness on this issue.
Case Reports Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES. 2025 Jun;31(6):600-602. doi: 10.14744/tjtes.2025.73576 Q31.02025
Pediatric methamphetamine poisoning: Case report of a one-year-old child
一例1岁幼儿甲基苯丙胺中毒病例报告 翻译改进
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DOI: 10.14744/tjtes.2025.73576 PMID: 40511761
摘要 中英对照阅读
甲基苯丙胺是一种安非他明的衍生物,在全球范围内被广泛滥用。它具有高度成瘾性,并作为中枢神经系统(CNS)的强大刺激剂起作用。由于其亲脂性质,甲基苯丙胺容易穿过血脑屏障,导致显著的神经功能障碍甚至神经元退化。甲基苯丙胺中毒的临床体征和症状因摄入剂量、给药途径、暴露时间(急性或慢性)以及使用方法等因素而异。常见的临床表现包括欣快感、精力充沛、失眠、焦虑、物质诱发的精神病、食欲下降、体重减轻、自信心增强、性欲增加、发热、心动过速、出汗、高血压、震颤、瞳孔散大、视物模糊和抽搐等。儿童尤其脆弱,他们的新陈代谢和神经系统比成人更敏感,因此毒性效应更为明显。药物和其他物质的意外摄入在儿科人群中较为常见,并可能导致严重的健康并发症。因此,医疗保健专业人员应及时准确地评估和管理此类中毒病例。本案例报告介绍了某名一岁男童因误食口服冰毒后的临床发现、诊断过程及治疗管理。此外,该报告还强调了有效病例管理的关键方面,着重于预防措施以减少儿童意外摄入药物和其他物质的风险,并旨在提高对此问题的认识。
关键词:甲氨phetamine中毒; 病例报告; 一岁儿童
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